Being an island Cayo Largo is currently only accessible by Air or Sea. There are no plans to build a causeway to Cayo Largo.

By air:

The Vilo Acuña International Airport in Cayo Largo del Sur is equipped to accept large scale aircraft and fulfils all security requirements set out by the International Civil Aviation Organization (ICAO), radio-navigation support, and has the capacity to attend to 300 passengers an hour. It receives aircraft from Frankfurt, Milan, Montreal, and Toronto. There are daily flights departing for and arriving from Havana. Additionally, there are weekly excursions to other major resorts in the country such as Varadero, Trinidad, Pinar del Río, Cienfuegos and Santiago de Cuba.

By sea:

Cayo Largo del Sur Yacht Marina offers immigration, customs and on board services.

Coordinates : 21°37'.0 N, 81°34'.0 W

Radio communication : VHF 16, 19A US & HF 7821.0

Tel.: (53) 45 248213 & 248133

Fax : (53) 45 248212 & 248133